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ELECTRONIC MOSQUITO

A MEMS-based Blood Sampling Device for Blood Analysis and Drug Delivery Applications

         

The research project "Electronic Mosquito" (or simply "e-MosquitoTM") is a Micro Electromechanical Systems (MEMS)-based device for semi-invasive blood sampling and analysis, which resembles the operation of a mosquito. At a miniature scale the proposed system does penetrate the skin to extract a static blood sample for further analysis. The extent of this penetration, and particularly the fact that it can be made painless, is particularly attractive for such applications as automated glucose analysis for closed-loop control of insulin infusion (artificial pancreas), continuous drug monitoring, or even periodic DNA analysis for security and identification purposes.

       
Press Releases:
  Camera in a pill offers doctors a look at your inner space. In The Globe & Mail, April 2005
  Nanotechnology Takes Medical Intervention to a New Level. In: R & D Magazine, October 2004.
 

Taking Control of Diabetes: "Electronic Mosquito" gives flight to an innovative way to measure glucose levels and deliver insulin. In: Canadian Microelectronic Corporation (CMC) magazine IMPACT Success Stories, January 2004.

   
Awards:
  eMosquitoTM: An Actuated Microneedle for Automated Blood Sampling, Giorgio Gattiker. University of Calgary MEMS Scholarship 2004 Winner.
   
Related Technical Publications:
1. G. Gattiker, M. Mintchev, and K.V.I.S. Kaler, A MicraGEM-based Microactuator Chip for Blood Sampling and Drug Delivery Applications, presented at ESSDERC-ESSCIRC 2005, Grenoble, France, 2005.
2.

Gattiker G, Kaler KVIS, and Mintchev MP. Electronic Mosquito: Designing a Semi-Invasive Microsystem for Blood Sampling, Analysis and Drug Delivery Applications. Journal of Microsystem Technologies, 2005, (in print).

3.

Giorgio Gattiker, Karan Kaler, and Martin Mintchev. Microactuation of Suspended MEMS Beams. In: Proc. of the 2005 IEEE International Symposium on Circuits and Systems (ISCAS 2005), Kobe, Japan, May 23 - 26, 2005.

4. Gattiker G, Kaler KVIS, and Mintchev MP. “ELECTRONIC MOSQUITO”: Prototyping a MEMS Device for Blood Sampling, Analysis, and Drug Delivery Purposes. In: Proc. of the 9th International Conference on the Commercialization of Micro and Nano Systems (COMS), Edmonton, Alberta, Canada, Aug 29 – Sept 2, 2004.
5. Gattiker GE, Kaler KVIS and Mintchev MP. Electronic Mosquito: Designing a Semi-Invasive Microsystem for Blood Sampling, Analysis and Drug Delivery Applications. In: Proc. of the IEEE Symposium on MEMS Design, Test, Integration and Packaging, Montreux, Switzerland, June 2004.
6. Gattiker G, Aggarwal P, Kaler KVIS, Mintchev MP. Electronic Mosquito: A Semi-Invasive MEMS for Blood Sampling, Analysis and Drug Delivery. In: Proceedings of the ASM/IEEE International Conference on Bio-, Micro-, Nanosystems, N.Y., N.Y., July 7-10, 2003.
7. LaFrenz J, Gattiker G, Kaler KVIS, and Mintchev MP. Starting from Scratch: Creating an Information Technology Infrastructure for MEMS-Related Research and Development. International Journal of Information Theories and Applications, 10(3), 330-6, 2003.
   
Provisional Patent Application:
 

Gattiker G, Kaler KVIS, Mintchev MP. “Electronic Mosquito”: A Semi-Invasive Automated Microsystem for Blood Sampling, Analysis and Drug Delivery Applications. US Provisional, November 2003.

   

Funding:

 
  CMC: Canadian Microelectronic Corporation
  NSERC: National Sciences and Engineering Research Council of Canada
  COVENTOR: MEMS Software for design of RF, Microfluidics, Sensors, and Optical Devices
  University of Calgary
         
Contact:      
         
  Martin P. Mintchev, Ph.D., P.Eng., Professor of Electrical Engineering      
  Karan V.I.S. Kaler, Ph.D., P.Eng., Professor of Electrical Engineering      
  Giorgio Gattiker, PhD Candidate, Electrical Engineering      
         
 

Department of Electrical and Computer Engineering, University of Calgary
2500, University Drive, N.W., Calgary, Alberta, Canada, T2N 1N4
Phone: +1-403-220-5806; Fax: +1-403-282-6855